Testicular histology after intestinal pedicle flap (cecum) apposition in rats.

Development of an irradiated rodent model to study flap revascularization.

OBJECTIVE To develop a reproducible free-flap animal model to study the effects of irradiation on flap revascularization. DESIGN After institutional animal care and use committee review and approval, 16 Sprague-Dawley rats were subjected to either 23- or 40-Gy electron beam irradiation to their ventral abdominal wall. After a recovery period, the animals then underwent a ventral fasciocutaneo...

Evaluating revascularization and flap survival using vascular endothelial growth factor in an irradiated rat model.

OBJECTIVE To evaluate the role of vascular endothelial growth factor (VEGF) plasmid DNA (pDNA) in improving flap revascularization in a previously developed rat model. Our hypothesis was that the uptake and expression of VEGF pDNA in the wound bed would improve revascularization and flap viability. DESIGN Twenty-eight male Sprague-Dawley rats received a total dose of 40 Gy electron beam radia...

Paramedian Forehead Flap Raised in the Base of Previously Used Median Forehead Flap Pedicle

The influence of type of vascular pedicle occlusion on the viability of skin island flaps: a postoperative quantitative assessment of flap survival in an experimental model in rats.

PURPOSE To evaluate the role of pedicle occlusion on the viable area of a skin island flap. METHODS An epigastric skin island flap was performed in 160 Wistar rats. The animals were randomly divided into four groups: G-1: occlusion of inferior epigastric artery; G-2: inferior epigastric vein; G-3: inferior epigastric vessels (artery/vein). At varying times postoperatively (2,3,4,5th day), ani...

The effect of 2 sealants (FloSeal and Tisseel) on fasciocutaneous flap revascularization.

BACKGROUND Fasciocutaneous tissue transfer is one of the most common procedures performed in head and neck reconstructive surgery. These composite tissues can be transferred as either a free flap or a pedicled flap. Free tissue transfer has become the reconstructive modality of choice following head and neck oncologic ablation. Synthetic tissue adhesives and hemostatic agents are rapidly gainin...